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Effect of coffee intake on oxidative stress in periodontal tissues
https://asahi-u.repo.nii.ac.jp/records/10195
https://asahi-u.repo.nii.ac.jp/records/101955048cb92-4704-4acb-a9fa-6668347393fc
| アイテムタイプ | 朝日大学 教育・研究業績(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-01-18 | |||||
| タイトル | ||||||
| タイトル | Effect of coffee intake on oxidative stress in periodontal tissues | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_1843 | |||||
| 資源タイプ | other | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 業績分類 | ||||||
| 値 | 学会発表 | |||||
| 教員氏名 |
東, 哲司
× 東, 哲司 |
|||||
| 発行、発表雑誌等、又は発表学会等の名称 | ||||||
| 値 | The 96th General Session of the IADR | |||||
| 単著、共著の別 | ||||||
| 値 | 共同 | |||||
| 発行又は発表の年月 | ||||||
| 日付 | 2018-07-25 | |||||
| 概要 | ||||||
| 値 | In this study, we aimed to examine the effect of coffee intake, an antioxidant substance, on the increase in oxidative stress in periodontal tissue with aging. Male Fischer 344 rats (n=25, 8 weeks old) were divided into 3 groups: 0.63% coffee diet (group A, n = 8), 1.36% coffee diet (Group B, n = 9), and normal diet (C group, n = 8). The OXY adsorbent level was significantly higher in Group A and Group B than that in Group C (P <0.05). The number of 8-OHdG positive cells was significantly lower in group B than that in group C (P <0.05). The number of nuclear Nrf2 was significantly higher in group B than that in group C (P <0.05). Intake of coffee inhibited the increase in oxidative stress in periodontal tissues with aging through Nrf2/antioxidant defense pathway. | |||||
