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Serum microRNAs and chronic periodontitis: A case-control study
https://asahi-u.repo.nii.ac.jp/records/11253
https://asahi-u.repo.nii.ac.jp/records/1125368fe89c2-e6f0-41de-9875-8a4f780d46d1
| Item type | 朝日大学 教育・研究業績(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-11-21 | |||||
| タイトル | ||||||
| タイトル | Serum microRNAs and chronic periodontitis: A case-control study | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_1843 | |||||
| 資源タイプ | other | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 業績分類 | ||||||
| 値 | 学術雑誌論文 | |||||
| 教員氏名 |
友藤, 孝明
× 友藤, 孝明 |
|||||
| 発行、発表雑誌等、又は発表学会等の名称 | ||||||
| 値 | Arch Oral Biol | |||||
| 巻 | ||||||
| 値 | 101 | |||||
| 掲載ページ | ||||||
| 値 | 57-63 | |||||
| 単著、共著の別 | ||||||
| 値 | 共著 | |||||
| 発行又は発表の年月 | ||||||
| 日付 | 2019-05 | |||||
| ISSN | ||||||
| 値 | 0003-9969 | |||||
| 概要 | ||||||
| 値 | An association is present between periodontitis and rates of expression of certain microRNAs (miRNAs) in periodontal tissue. We performed a case-control study in patients with chronic periodontitis to investigate serum miRNA levels. We enrolled 30 healthy patients without periodontitis and 30 patients with chronic periodontitis. Microarray demonstrated seven miRNAs that were expressed <1/1.5 or >1.5 in the control group compared to the periodontitis group (p < 0.05). Real-time PCR showed that hsa-miR-664a-3p, hsa-miR-501-5p, and hsa-miR-21-3p were higher in the periodontitis group than the control group (p < 0.05). Hsa-miR-664a-3p, hsa-miR-501-5p, and hsa-miR-21-3p are candidate serum biomarkers for chronic periodontitis. | |||||
