{"created":"2023-06-23T12:20:25.917366+00:00","id":11745,"links":{},"metadata":{"_buckets":{"deposit":"d4232f32-40ae-406a-9793-fa7ef528c699"},"_deposit":{"created_by":19,"id":"11745","owners":[19],"pid":{"revision_id":0,"type":"depid","value":"11745"},"status":"published"},"_oai":{"id":"oai:asahi-u.repo.nii.ac.jp:00011745","sets":["64:123"]},"author_link":["14976"],"item_10_creator_30":{"attribute_name":"教員氏名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"江原, 雄一"}],"nameIdentifiers":[{"nameIdentifier":"14976","nameIdentifierScheme":"WEKO"}]}]},"item_10_date_36":{"attribute_name":"発行又は発表の年月","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-10"}]},"item_10_textarea_29":{"attribute_name":"業績分類","attribute_value_mlt":[{"subitem_textarea_value":"学会発表"}]},"item_10_textarea_31":{"attribute_name":"発行、発表雑誌等、又は発表学会等の名称","attribute_value_mlt":[{"subitem_textarea_value":"第64回日本口腔外科学会総会・学術大会"}]},"item_10_textarea_35":{"attribute_name":"単著、共著の別","attribute_value_mlt":[{"subitem_textarea_value":"共同発表"}]},"item_10_textarea_42":{"attribute_name":"概要","attribute_value_mlt":[{"subitem_textarea_value":"我々はC3Hマウス口腔扁平上皮癌細胞株Sq1979の放出するIL-1αが同系マウス由来の線維芽細胞（10T1/2）による抗CD3抗体刺激脾細胞のIFN-γ産生能の有意な抑制作用を突き止めIL-1αが間葉系細胞を介する免疫抑制機構を促進することを示した。腫瘍組織では脈管系の分布や間質組織との相互作用で腫瘍細胞の置かれる栄養条件等が部位特異的に異なることが考えられ異なる微細環境におけるOSCCのIL-1α発現調節機構の検討目的で低血清濃度や低酸素状態がSq1979細胞のIL-1α産生と免疫抑制作用にどのような影響を及ぼすのかを検討した。"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"other","resourceuri":"http://purl.org/coar/resource_type/c_1843"}]},"item_title":"低血清環境におけるマウス口腔扁平上皮癌細胞株のIL-1α産生能と免疫抑制作用の上","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"低血清環境におけるマウス口腔扁平上皮癌細胞株のIL-1α産生能と免疫抑制作用の上"}]},"item_type_id":"10","owner":"19","path":["123"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-11-26"},"publish_date":"2019-11-26","publish_status":"0","recid":"11745","relation_version_is_last":true,"title":["低血清環境におけるマウス口腔扁平上皮癌細胞株のIL-1α産生能と免疫抑制作用の上"],"weko_creator_id":"19","weko_shared_id":-1},"updated":"2023-06-23T13:16:01.569251+00:00"}