@article{oai:asahi-u.repo.nii.ac.jp:00013578, author = {UNO, MITSUNORI and KAWAI, RYOSUKE and SAWADA, TOSHIKO and SAWANO, MIKU and HIGA, TASUKU and OKA, TOSHIO and KURACHI, MASAKAZU and ISHIGAMI, HAJIME}, issue = {2021-06}, journal = {2021-06}, month = {2021-06, 2021-09-22}, note = {In the present study, we investigated circadian variation in the concentration of salivary α-amylas (e CsA), which is known to be affected by stress, using a salivary amylase monitor with a chip. The CsA was measured three times a day( diurnal; morning, noon, and evening), three times a week (daily; Monday, Wednesday, and Friday) and three times a month (weekly; 1st, 2nd, and 3rd weeks). Ten healthy male participants aged 25‒30 years were recruited. A three-way analysis of variance (ANOVA; [diurnal, daily, and weekly]) was used. Multiple comparisons between groups were performed using the Tukey honest significant difference post-hoc test. The ANOVA found a significant main effect in diurnal and daily measurements. When the CsA was compared within the diurnal groups, post-hoc test found that the values in the noon and evening were significantly higher than those in the morning (p<0.01). Similarly, the CsA values on Fridays were significantly lower than those on Mondays. These results suggest that CsA shows a diurnal and daily fluctuation.}, pages = {2021-06--2021-06}, title = {Circadian variation in the concentration of salivary α-amylase in healthy humans}, volume = {2021-06}, year = {} }