{"created":"2023-06-23T12:13:39.998699+00:00","id":1809,"links":{},"metadata":{"_buckets":{"deposit":"ff0c116b-7adb-4bcd-82a4-5998252958ea"},"_deposit":{"created_by":19,"id":"1809","owners":[19],"pid":{"revision_id":0,"type":"depid","value":"1809"},"status":"published"},"_oai":{"id":"oai:asahi-u.repo.nii.ac.jp:00001809","sets":["64:123"]},"author_link":["2268"],"item_10_creator_30":{"attribute_name":"教員氏名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"川木, 晴美"}],"nameIdentifiers":[{"nameIdentifier":"2268","nameIdentifierScheme":"WEKO"}]}]},"item_10_date_36":{"attribute_name":"発行又は発表の年月","attribute_value_mlt":[{"subitem_date_issued_datetime":"2013-10-24"}]},"item_10_text_38":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_text_value":"1523-4681"}]},"item_10_text_41":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_text_value":"24155087"}]},"item_10_textarea_29":{"attribute_name":"業績分類","attribute_value_mlt":[{"subitem_textarea_value":"学術雑誌論文"}]},"item_10_textarea_31":{"attribute_name":"発行、発表雑誌等、又は発表学会等の名称","attribute_value_mlt":[{"subitem_textarea_value":"Journal of Bone and Mineral Research"}]},"item_10_textarea_32":{"attribute_name":"巻","attribute_value_mlt":[{"subitem_textarea_value":"印刷中"}]},"item_10_textarea_33":{"attribute_name":"号","attribute_value_mlt":[{"subitem_textarea_value":"印刷中"}]},"item_10_textarea_35":{"attribute_name":"単著、共著の別","attribute_value_mlt":[{"subitem_textarea_value":"共著"}]},"item_10_textarea_42":{"attribute_name":"概要","attribute_value_mlt":[{"subitem_textarea_value":"（担当）研究計画立案、実験指導、実験実施（概要）ニワトリ頭蓋骨由来より骨細胞を単離して実験に用い、圧縮力を負荷した骨細胞ではCCN2の発現が上昇しアポトーシスが誘導されることを見出した。その際ERK1/2経路が活性化し、CCN2中和抗体および阻害剤による実験から、圧縮力により発現が促進されたCCN2がERK1/2経路の活性化を促進してアポトーシスを誘導することを明らかにした。（共著）星健治, 川木晴美, 高橋一郎, 竹下信郎, 清流正弘, Murshid SA, 増田泰輔, 穴田貴久, 加藤龍司, 北浦英樹, 鈴木治, 山本照子"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"other","resourceuri":"http://purl.org/coar/resource_type/c_1843"}]},"item_title":"Compressive Force-Produced CCN2 Induces Osteocyte Apoptosis Through ERK1/2 Pathway.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Compressive Force-Produced CCN2 Induces Osteocyte Apoptosis Through ERK1/2 Pathway."}]},"item_type_id":"10","owner":"19","path":["123"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-02-10"},"publish_date":"2015-02-10","publish_status":"0","recid":"1809","relation_version_is_last":true,"title":["Compressive Force-Produced CCN2 Induces Osteocyte Apoptosis Through ERK1/2 Pathway."],"weko_creator_id":"19","weko_shared_id":-1},"updated":"2023-06-23T15:00:38.032663+00:00"}