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Abnormal Chondrocyte Differentiation in Post-natal Cartilage Calcification Insufficient Rat
https://asahi-u.repo.nii.ac.jp/records/5592
https://asahi-u.repo.nii.ac.jp/records/5592537549cb-9b11-4dea-a8fa-d0c33efdfb68
| Item type | 朝日大学 教育・研究業績(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-10-10 | |||||
| タイトル | ||||||
| タイトル | Abnormal Chondrocyte Differentiation in Post-natal Cartilage Calcification Insufficient Rat | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_1843 | |||||
| 資源タイプ | other | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 業績分類 | ||||||
| 値 | 学会発表 | |||||
| 教員氏名 |
永山, 元彦
× 永山, 元彦 |
|||||
| 発行、発表雑誌等、又は発表学会等の名称 | ||||||
| 値 | 93rd General Session & Exhibition of the IADR/44th Annual Meeting of the AADR/39th Annual Meeting of the CADR | |||||
| 単著、共著の別 | ||||||
| 値 | 共同発表 | |||||
| 発行又は発表の年月 | ||||||
| 日付 | 2015-03-13 | |||||
| 概要 | ||||||
| 値 | Contribution: Presenter, To determine whether Ihh regulates those processes during post-natal life, we studied these morphological characteristics of chondrocytes at cranial base synchondrosis and condylar cartilage of cartilage calcification insuficient (CCI) rats compared to normal SD rats.CCI rats showed abnormal synchondrosis including longitudinally wider length of intra-sphenoidal and spheno-occipital synchondrosis compared to the normal SD rats. CCI rats also exhibited morphological defects surface or reduced cartilage of mandibular condyle based of the histological and molecular biological findings. The data demonstrate that CCI rats affect their endochondral ossification due to excessive Ihh signaling, which results in hyper proliferating but feed-back arrest of chondrocyte differentiation to remain the layer of chondrocytes in post-natal development. | |||||
