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Validity of a new kit measuring salivary lactate dehydrogenase level for screening gingivitis

https://asahi-u.repo.nii.ac.jp/records/7744
https://asahi-u.repo.nii.ac.jp/records/7744
5c5fccb3-259e-41b3-be3a-a466e113e515
Item type 朝日大学 教育・研究業績(1)
公開日 2017-10-13
タイトル
タイトル Validity of a new kit measuring salivary lactate dehydrogenase level for screening gingivitis
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_1843
資源タイプ other
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
業績分類
値 学術雑誌論文
教員氏名 友藤, 孝明

× 友藤, 孝明

WEKO 11234

友藤, 孝明

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発行、発表雑誌等、又は発表学会等の名称
値 Dis Markers
掲載ページ
値 9547956
単著、共著の別
値 共著
発行又は発表の年月
日付 2017-02-26
ISSN
値 0278-0240
PubMed番号
値 28337048
概要
値 The aim of this study was to determine the usefulness of a new kit that can evaluate salivary lactate dehydrogenase (LD) level in real time for screening gingivitis. The study included 70 systemic healthy volunteers [29 males and 41 females; mean age ± SD: 24.1 ± 2.6 years]. Resting saliva was collected from each participant and LD level was evaluated in real time using the kit (a color-changing sheet with an integer scale ranging from 1 to 10). A dentist measured probing pocket depth, clinical attachment level, and the proportion of sites with bleeding on probing (% BOP) at six sites on all teeth. Gingivitis was diagnosed when the BOP value was ≥20%. Salivary LD level was positively correlated with mean % BOP (odds ratio: 1.47, 95% confidence interval: 1.132-1.916, and P < 0.001) in a logistic regression model. The sensitivity and specificity of the kit were 0.89 and 0.98, respectively, at a cut-off value of 8.0 for LD level. In conclusion, the new kit for measurement of salivary LD level may be a useful tool to screen for gingivitis in young adults, which contributes to early detection of future periodontitis.
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