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Validity of a new kit measuring salivary lactate dehydrogenase level for screening gingivitis
https://asahi-u.repo.nii.ac.jp/records/7744
https://asahi-u.repo.nii.ac.jp/records/77445c5fccb3-259e-41b3-be3a-a466e113e515
| Item type | 朝日大学 教育・研究業績(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-10-13 | |||||
| タイトル | ||||||
| タイトル | Validity of a new kit measuring salivary lactate dehydrogenase level for screening gingivitis | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_1843 | |||||
| 資源タイプ | other | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 業績分類 | ||||||
| 値 | 学術雑誌論文 | |||||
| 教員氏名 |
友藤, 孝明
× 友藤, 孝明 |
|||||
| 発行、発表雑誌等、又は発表学会等の名称 | ||||||
| 値 | Dis Markers | |||||
| 掲載ページ | ||||||
| 値 | 9547956 | |||||
| 単著、共著の別 | ||||||
| 値 | 共著 | |||||
| 発行又は発表の年月 | ||||||
| 日付 | 2017-02-26 | |||||
| ISSN | ||||||
| 値 | 0278-0240 | |||||
| PubMed番号 | ||||||
| 値 | 28337048 | |||||
| 概要 | ||||||
| 値 | The aim of this study was to determine the usefulness of a new kit that can evaluate salivary lactate dehydrogenase (LD) level in real time for screening gingivitis. The study included 70 systemic healthy volunteers [29 males and 41 females; mean age ± SD: 24.1 ± 2.6 years]. Resting saliva was collected from each participant and LD level was evaluated in real time using the kit (a color-changing sheet with an integer scale ranging from 1 to 10). A dentist measured probing pocket depth, clinical attachment level, and the proportion of sites with bleeding on probing (% BOP) at six sites on all teeth. Gingivitis was diagnosed when the BOP value was ≥20%. Salivary LD level was positively correlated with mean % BOP (odds ratio: 1.47, 95% confidence interval: 1.132-1.916, and P < 0.001) in a logistic regression model. The sensitivity and specificity of the kit were 0.89 and 0.98, respectively, at a cut-off value of 8.0 for LD level. In conclusion, the new kit for measurement of salivary LD level may be a useful tool to screen for gingivitis in young adults, which contributes to early detection of future periodontitis. | |||||