{"created":"2023-06-23T12:17:32.166256+00:00","id":7931,"links":{},"metadata":{"_buckets":{"deposit":"e75d3885-f6e0-410b-a56e-4576ec95e762"},"_deposit":{"created_by":19,"id":"7931","owners":[19],"pid":{"revision_id":0,"type":"depid","value":"7931"},"status":"published"},"_oai":{"id":"oai:asahi-u.repo.nii.ac.jp:00007931","sets":["64:123"]},"author_link":["11421"],"item_10_creator_30":{"attribute_name":"教員氏名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中尾, 寿奈"}],"nameIdentifiers":[{"nameIdentifier":"11421","nameIdentifierScheme":"WEKO"}]}]},"item_10_date_36":{"attribute_name":"発行又は発表の年月","attribute_value_mlt":[{"subitem_date_issued_datetime":"2016-03-05"}]},"item_10_textarea_29":{"attribute_name":"業績分類","attribute_value_mlt":[{"subitem_textarea_value":"学会発表"}]},"item_10_textarea_31":{"attribute_name":"発行、発表雑誌等、又は発表学会等の名称","attribute_value_mlt":[{"subitem_textarea_value":"平成27年度　第4回超音波分子診断治療研究会"}]},"item_10_textarea_35":{"attribute_name":"単著、共著の別","attribute_value_mlt":[{"subitem_textarea_value":"共同発表"}]},"item_10_textarea_42":{"attribute_name":"概要","attribute_value_mlt":[{"subitem_textarea_value":"歯周病は細菌感染による炎症疾患で骨芽細胞はグラム陰性菌のLPSによりケモカインを発現し炎症細胞の遊走を誘導する。LIPUSは骨代謝促進から骨折治療に臨床応用されている。骨芽細胞にLPS刺激を与えたところケモカインCXCL1, CXCL10とCCL2のmRNA発現量は著しく上昇し、そのうちCXCL1とCXCL10の発現はLIPUS 共刺激にて有意に抑制された。NFκB活性、上流キナーゼの活性、TLR４の発現、TLR4/MyD88複合体形成等LPS誘導シグナル伝達へのLIPUSの影響を検討した。"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"other","resourceuri":"http://purl.org/coar/resource_type/c_1843"}]},"item_title":"低出力超音波刺激 (LIPUS) は骨芽細胞のLPS誘導性炎症反応を抑制する","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"低出力超音波刺激 (LIPUS) は骨芽細胞のLPS誘導性炎症反応を抑制する"}]},"item_type_id":"10","owner":"19","path":["123"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-14"},"publish_date":"2017-10-14","publish_status":"0","recid":"7931","relation_version_is_last":true,"title":["低出力超音波刺激 (LIPUS) は骨芽細胞のLPS誘導性炎症反応を抑制する"],"weko_creator_id":"19","weko_shared_id":-1},"updated":"2023-06-23T14:03:32.267813+00:00"}