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Effect of Topical Anesthesia Using an Adhesive Patch and Anesthetic Solution
https://asahi-u.repo.nii.ac.jp/records/8629
https://asahi-u.repo.nii.ac.jp/records/86296441c3c7-7899-48ef-98ca-de5726c5d0f4
| Item type | 朝日大学 教育・研究業績(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-01-10 | |||||
| タイトル | ||||||
| タイトル | Effect of Topical Anesthesia Using an Adhesive Patch and Anesthetic Solution | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_1843 | |||||
| 資源タイプ | other | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 業績分類 | ||||||
| 値 | 学術雑誌論文 | |||||
| 教員氏名 |
岸本, 敏幸
× 岸本, 敏幸 |
|||||
| 発行、発表雑誌等、又は発表学会等の名称 | ||||||
| 値 | Anesthesia Progress | |||||
| 巻 | ||||||
| 値 | 64 | |||||
| 号 | ||||||
| 値 | 2 | |||||
| 掲載ページ | ||||||
| 値 | 73-79 | |||||
| 単著、共著の別 | ||||||
| 値 | 共著 | |||||
| 概要 | ||||||
| 値 | （概要）We analyzed trigeminal somatosensory evoked potentials (TSEP) to the alveolar mucosa to investigate the efficacy of an amide local anesthetic, 2% lidocaine hydrochloride with 12.5 µg/mL epinephrine, (Lido) as a topical anesthetic. Eighteen consenting healthy adult volunteers were enrolled. A volume of 0.06mL or Lido ,0.06 g of 20% benzocaine (Benzo), or 0.06 mL of physiological saline (Control) were instilled onto a hemostatic adhesive patch, which were then applied to the alveolar mucosa at the maxillary right canine for 5 min. An electrical stimulus about five times that of the sensory threshold was applied using a surface stimulation electrode and the TSEP was recorded immediately, 5 min, and 10 min after removal of the patch. Positive P125 and P310 peaks and negative N100 and N340 peaks were observed as a result of the electrical stimulation. A significant decrease in the percentage change in amplitude of N100-P125 was observed in the Lido treatment immediately, 5 min, and 10 min after patch removal. In the Lido treatment, TSEP amplitude at N100-P125 decreased significantly, suggesting that topical anesthesia produced by an amide local anesthetic may have a topical anesthetic effect as potent as that produced by an ester local anesthetic. | |||||
