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  1. 学術雑誌論文
  2. 歯学部
  3. 附属村上記念病院

Efficacy of butylscopolamine in obtaining clear MR image for intensity-modulated radiotherapy for prostate cancer.

https://asahi-u.repo.nii.ac.jp/records/9127
https://asahi-u.repo.nii.ac.jp/records/9127
808b3874-1897-4212-bfc3-35c72b800e0f
名前 / ファイル ライセンス アクション
24056324_3-4_1922_2017.pdf 24056324_3-4_1922_2017 (674.8 kB)
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Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-01-23
タイトル
タイトル Efficacy of butylscopolamine in obtaining clear MR image for intensity-modulated radiotherapy for prostate cancer.
タイトル
タイトル Efficacy of butylscopolamine in obtaining clear MR image for intensity-modulated radiotherapy for prostate cancer.
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Tanaka, Osamu

× Tanaka, Osamu

WEKO 12611

Tanaka, Osamu

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Komeda, Hisao

× Komeda, Hisao

WEKO 12612

Komeda, Hisao

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Tamaki, Masayoshi

× Tamaki, Masayoshi

WEKO 12628

Tamaki, Masayoshi

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Seike, Kensaku

× Seike, Kensaku

WEKO 12629

Seike, Kensaku

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所属
Department of Radiation Oncology, Gifu Municipal Hospital
所属
Department of Urology, Gifu Municipal Hospital
所属
Department of Urology, Gifu Municipal Hospital
所属
Department of Urology, Gifu Municipal Hospital
書誌情報 en : Technical Innovations & Patient Support in Radiation Oncology

巻 3-4, p. 19-22, 発行日 2017
出版者
Elsevier
抄録
内容記述タイプ Abstract
内容記述 Purpose
The use of butylscopolamine in magnetic resonance imaging (MRI) of the prostate is controversial in the context of diagnostic imaging where local invasion and the presence of metastases are evaluated. However, in radiation oncology, MRI is performed as part of the simulation process, and the objectives differ to the diagnostic setting. MRI is primarily used for accurate target delineation; hence, the use of an agent to reduce intestinal peristalsis and increase image quality may be beneficial. The impact of butylscopolamine on MRI for radiation oncology purposes has not previously been described. The aim of this study was to evaluate the efficacy of butylscopolamine in MRI acquired for radiation oncology simulation of the prostate.
Methods and materials
In total, 67 patients were enrolled in this study. Thirty-five patients received intramuscular injection of butylscopolamine (group A) and 32 patients did not (group B). Visualization of the prostate outline and detection of fiducial gold markers (GMs) in the prostate were evaluated on MRI. Two blinded radiation oncologists (ROs) and one radiation technologist (RT) scored the image quality of the detection of prostate outline and recognition of GMs in the prostate on a scale of 1–5 (1 = poor; 5 = excellent), and the results were evaluated using Mann–Whitney U test and p < 0.05 was considered as statistically significant.
Results
On MRI, group A was statistically superior to group B in terms of fiducial marker detection by two ROs (p < 0.01). However, there was no significant difference in RT scoring. Furthermore, on MRI, group A was statistically superior to group B in terms of the detection of the prostate outline by an RT.
Conclusions
Butylscopolamine is effective with respect to detection of the prostate outline and GM recognition (without endorectal coil). The addition of butylscopolamine is simple and cost efficient. We recommend the use of butylscopolamine routinely to obtain good MR images, particularly in the detection of GMs.
ISSN
収録物識別子タイプ ISSN
収録物識別子 2405-6324
フォーマット
内容記述タイプ Other
内容記述 application/pdf
関連サイト
識別子タイプ URI
関連識別子 https://www.sciencedirect.com/science/article/pii/S2405632417300112
関連名称 出版社版(ScienceDirect)
著者版フラグ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
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