@article{oai:asahi-u.repo.nii.ac.jp:00009137,
 author = {Tanaka, Osamu and Hayashi, Shinya and Matsuo, Masayuki and Nakano, Masahiro and Kubota, Yasuaki and Maeda, Sunaho and Ohtakara, Kazuhiro and Deguchi, Takashi and Hoshi, Hiroaki},
 issue = {1},
 journal = {Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
 month = {Jul},
 note = {application/pdf, Purpose
To compare the dosimetric results between MRI-based and TRUS-based preplanning in permanent prostate brachytherapy, and to estimate the accuracy of MRI-based preplanning by comparing with CT/MRI fusion-based postimplant dosimetry.
Methods and materials
Twenty-one patients were entered in this prospective study with written informed consent. MRI-based and TRUS-based preplanning were performed. The seed and needle locations were identical according to MRI-based and TRUS-based preplanning. MRI-based and TRUS-based preplanning were compared using DVH-related parameters. Following brachytherapy, the accuracy of the MRI-based preplanning was evaluated by comparing it with CT/MRI fusion-based postimplant dosimetry.
Results
Mean MRI-based prostate volume was slightly underestimated (0.73 cc in mean volume) in comparison to TRUS-based volume. There were no significant differences in the mean DVH-related parameters except with rectal V100(cc) between TRUS-based and MRI-based preplanning. Mean rectal V100(cc) was 0.74 cc in TRUS-based and 0.29 cc in MRI-based preplanning, respectively, and the values demonstrated a statistical difference.
There was no statistical difference in mean rectal V150(cc), and rectal V100(cc) between MRI-based preplanning and CT/MRI fusion-based postimplant dosimetry.
Conclusion
Prostate volume estimation and DVH-related parameters in MRI-based preplanning were almost identical to TRUS-based preplanning. From the results of CT/MRI fusion-based postimplant dosimetry, MRI-based preplanning was therefore found to be a reliable and useful modality, as well as being helpful for TRUS-based preplanning. MRI-based preplanning can more accurately predict postimplant rectal dose than TRUS-based preplanning.},
 pages = {115--120},
 title = {MRI-based preplanning in low-dose-rate prostate brachytherapy.},
 volume = {88},
 year = {2008}
}