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Carbonate Apatite (CAp) における骨伝導能の基礎的研究
https://asahi-u.repo.nii.ac.jp/records/14030
https://asahi-u.repo.nii.ac.jp/records/1403086175bd7-2ab5-4656-9427-b8a2ebc15e4a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
gifushika333_197206_2007 (15.9 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2023-02-18 | |||||
| タイトル | ||||||
| タイトル | Carbonate Apatite (CAp) における骨伝導能の基礎的研究 | |||||
| タイトル | ||||||
| タイトル | Fundamental Study of Osteoconduction by Carbonate Apatite (CAp) | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 骨芽細胞 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 骨形成 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 骨導 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 細胞分化 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 破骨細胞 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 歯周組織再生誘導法 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 多血小板血漿 | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Carbonate apatite (CAp) | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Plasma Rich in Platelets (PRP) | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Osteoconduction | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Carbonate apatite (CAp) | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Plasma Rich in Platelets (PRP) | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Osteoconduction | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
高木, 宏太
× 高木, 宏太× 梶本, 忠保× 伊藤, 範明× 竹内, 宏× 山本, 宏治 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 6590 | |||||
| 姓名 | TAKAGI, KOHTA | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 4713 | |||||
| 姓名 | KAJIMOTO, TADAYASU | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 5916 | |||||
| 姓名 | ITO, NORIAKI | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 4274 | |||||
| 姓名 | TAKEUCHI, HIROSHI | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 5486 | |||||
| 姓名 | YAMAMOTO, KOHJI | |||||
| 所属 | ||||||
| 値 | 朝日大学歯学部口腔機能修復学講座歯科補綴学分野 Department of Prosthodontics, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry |
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| 所属 | ||||||
| 値 | 朝日大学歯学部口腔機能修復学講座歯科補綴学分野 Department of Prosthodontics, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry |
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| 所属 | ||||||
| 値 | 朝日大学歯学部口腔機能修復学講座歯科補綴学分野 Department of Prosthodontics, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry |
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| 所属 | ||||||
| 値 | 口腔病態医療学講座口腔病理学分野 Department of Oral Pathology, Division of Oral Pathogenesis and Diseases Control, Asahi University School of Dentistry |
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| 所属 | ||||||
| 値 | 朝日大学歯学部口腔機能修復学講座歯科補綴学分野 Department of Prosthodontics, Division of Oral Functional Science and Rehabilitation, Asahi University School of Dentistry |
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| 書誌情報 |
岐阜歯科学会雑誌 en : The Journal of Gifu Dental Society 巻 33, 号 3, p. 197-206, 発行日 2007-02-20 |
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| 出版者 | ||||||
| 値 | 岐阜歯科学会 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Carbonate contenting apatite (CAp) has demonstrated the capacity to stimulate the bone, when it is applied during osteo-formation stage. However, in some way this ability to promote the bone growth continues unclear and in attempt to investigate this concern, it could be a theory involving the bone and its external soft tissue when a treatment is carried out. In this study, the granulate CAp was synthesized and added to experimentally animal alveolar mucous, as well as monitored with the objective to identify the characteristics and morphological changes during the organic response. A total of three dogs were selected and two incisions of 5mm were performed on both sides of the upper jaw, the incisions were situated in the alveolar mucous of the molars area. After that, two pockets were created, and a prepared CAp block was placed it in one of them considering this as control; whereas in the experimental pocket the CAp block and PRP were mixed with the intention of harmonized the combination. The sections studied and theirs surrounding zones were extirpated from the three dogs after two, four and eight weeks respectively. The samples were stained with Masson's modified process and observed by light microscope, scanning and transmission electron microscope (SEM, TEM) to realize the HE and kind of dispersion on the obtained region of new bone. The observation of CAp blocks and its surroundings zones by light microscope showed augmentation of granulomatous tissue. Furthermore, all specimens presented increase of apparent osteoblasts and a slightly difference of bone formation were demonstrated. The amounts of new bone in the experimental pockets (CAp plus PRP) were greater than in control pockets (CAp). In addition, the micrographs of SEM and TEM illustrated, that the apparent osteocytes were covered by high density collagen fibers. The studied CAp proved the ability to stimulate the osteoconstruction when it is applied it to the alveolar mucous. Nevertheless, the results obtained when CAp was combined with PRP exhibited a higher capacity to promote the cellular specialization and bone formation. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 物理化学的性状が骨アパタイトに類似し、弱酸中での溶解性がハイドロキシアパタイト（HA）に比べ著しく大きい炭酸含有アパタイト（CA）顆粒を合成し、これを実験動物の歯槽粘膜に填入し、経時的な組織応答の形態学的検索の面から検討した。軟部組織に填入したCAは、経時的に線維化しない特殊な組織形成を誘導した。その組織は幼若な肉芽組織様で、その組織中に骨芽細胞様細胞および破骨細胞様細胞の分化を誘導した。これら骨芽細胞様細胞は類骨様組織を形成した。Plasma Rich in Plateletsはそれらの細胞分化および類骨様組織形成能を促進させる作用があった。CAは骨形成のための前駆組織の分化と増殖を誘導する性状を有していることが示唆された。 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0385-0072 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00053070 | |||||
| 論文ID（NAID） | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | NAID | |||||
| 関連識別子 | 110006607230 | |||||
| 医中誌文献番号 | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | ICHUSHI | |||||
| 関連識別子 | 2007210221 | |||||
| フォーマット | ||||||
| 値 | application/pdf | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 見出し | ||||||
| 大見出し | 原著 | |||||
| 言語 | ja | |||||
| 見出し | ||||||
| 大見出し | ORIGINAL ARTICLES | |||||
| 言語 | en | |||||
