{"_buckets": {"deposit": "b9a2fe7b-ba89-44c8-9589-e23b1ba09a09"}, "_deposit": {"created_by": 21, "id": "5055", "owners": [21], "pid": {"revision_id": 0, "type": "depid", "value": "5055"}, "status": "published"}, "_oai": {"id": "oai:asahi-u.repo.nii.ac.jp:00005055", "sets": ["332"]}, "author_link": ["4278", "8583", "8584", "3973", "3971", "4134", "8585", "4128", "8586", "4279", "4101", "4185", "4126", "4925", "8582", "511"], "item_10002_biblio_info_77": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2010-10-20", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "95", "bibliographicPageStart": "91", "bibliographicVolumeNumber": "37", "bibliographic_titles": [{"bibliographic_title": "岐阜歯科学会雑誌"}, {"bibliographic_title": "The journal of Gifu Dental Society", "bibliographic_titleLang": "en"}]}]}, "item_10002_description_80": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "歯周組織に及ぼす喫煙の影響を検討する目的で、歯肉線維芽細胞へのニコチンの影響について検討した。歯肉線維芽細胞は通常の培地で24時間培養され、次に1μg/ml、0.1μg/ml、0.01μg/mlのニコチン含有培地で培養した。細胞増殖能を測定するために培養終了24時間前に3H-Thymidineを添加した。培養終了後に放射能計測を行い、細胞分裂能を観察した。さらに同様の培養後に細胞形態を観察した。また細胞骨格の観察の目的でFITC Phalloidinで染色し、ストレスファイバーの観察をおこなった。ニコチン添加1μg/ml群では有意に細胞増殖能が低下した。また1μg/ml群では細胞形態は紡錘型を呈していた。さらに細胞骨格のストレス線維は収縮し、粗になっていた。これらの結果から、歯肉線維芽細胞の増殖にニコチン摂取が抑制的に関与することが示唆された。", "subitem_description_type": "Abstract"}]}, "item_10002_full_name_75": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "3973", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "SHIBUTANI, TOSHIAKI"}]}, {"nameIdentifiers": [{"nameIdentifier": "4278", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "KANAYAMA, KEIICHI"}]}, {"nameIdentifiers": [{"nameIdentifier": "8584", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "UENO, KENICHIRO"}]}, {"nameIdentifiers": [{"nameIdentifier": "8585", "nameIdentifierScheme": "WEKO"}], "names": 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